产品货号：
Z30164
中文名称：
ZP3抗体
英文名称：
Anti-ZP3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZP3 Antibody |
| 指标别名 | Sperm receptor,Zona pellucida glycoprotein 3,Zona pellucida protein C,Zp 3,ZP3,ZP3A,ZP3A/ZP3B,ZP3B,ZPC |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | ZP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human ZP3(LRLMEENWNAEKRSPTFHLGDAAHLQAEIHT). |
| 实际分子量 | 47KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Zona pellucida sperm-binding protein 3,also known as zona pellucida glycoprotein 3 (Zp-3) or the sperm receptor,is a ZP module-containing protein that in humans is encoded by the ZP3 gene.It is mapped to 7q11.23.he zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo.It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development.The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction.The nascent protein contains a N-terminal signal peptide sequence,a conserved ZP domain,a C-terminal consensus furin cleavage site,and a transmembrane domain.It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.However,the requirement for furin cleavage in this process remains controversial based on mouse studies.A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus;however,sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome.Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3,including the above described variation,and maps closely to this gene. |
| Uniprot ID | P21754 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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